HP's global operations were directed from its headquarters in Palo Alto, California.
Its US operations were directed from its facility in an unincorporated area of Harris County, Texas, near Houston.
Its Latin America offices were in unincorporated Miami-Dade County, Florida.
Its Europe offices were in Meyrin, Switzerland, but it also had a research center in the Paris-Saclay cluster 20 km south of Paris, France.
Its Asia-Pacific offices were in Singapore.
It also had large operations in Leixlip, Ireland; Austin, Texas; Boise, Idaho; Corvallis, Oregon; Fort Collins, Colorado; Roseville, California; Saint Petersburg, Florida; San Diego, California; Tulsa, Oklahoma; Vancouver, Washington; Conway, Arkansas; and Plano, Texas.
In the UK, HP was based at a large site in Bracknell, Berkshire with offices in various UK locations, including a landmark office tower in London, 88 Wood Street.
Its acquisition of 3Com expanded its employee base to Marlborough, Massachusetts, where it has been manufacturing its convertible laptop series since late 2019.
The company also had a large workforce and numerous offices in Bucharest, Romania, and at Bangalore, India, to address their back end and IT operations.
MphasiS, which is headquartered at Bangalore, also enabled HP to increase their footprint in the city as it was a subsidiary of EDS which the company acquired.